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  3. Ascites in Liver Cancer: Understanding and Management

Ascites in Liver Cancer: Understanding and Management

Understand the impact of ascites in liver cancer. Explore treatment options and supportive care to manage symptoms and improve quality of life.

  • Liver Cancer
By Shreya Sanas 31st Jan '23 14th Apr '24

Overview

Ascites are the accumulation of fluid in the abdomen. It can be a liver cancer symptom or other conditions affecting the liver. In liver cancer, ascites can be caused by the tumor or the liver's inability to function correctly. 

Before ascites formation, you may have had liver metastases, enlarged abdominal lymph nodes, or a significant tumor load. The fluid accumulating in the abdomen can cause discomfort and abdominal swelling, leading to other complications such as infections. 

Read till the end to know as to why ascites form in Liver cancer, and what can be done to treat this condition.

Why do Ascites Form in Liver Cancer?

Ascites can form in liver cancer for several reasons. The tumor itself can cause the formation of ascites by blocking the flow of blood through the liver. This can lead to increased pressure in the portal vein, which carries blood from the intestines and spleen to the liver. The increased pressure can cause fluid to leak out of the blood vessels and into the abdominal cavity, leading to ascites.

The liver plays a vital role in maintaining the balance of fluids in the body. When the liver is not functioning correctly, it can accumulate fluid in the abdomen. In addition, liver cancer can cause the liver to perform poorly, which can also lead to the formation of ascites and can further lead to a liver transplant.

Dr. Shara Cohen, CEO and Founder of Cancer Care Parcel, has quoted that - 

"Liver malignancy can decrease liver function. And cancer cells replaces liver tissue, resulting in a reduced liver function. The liver produces albumin, which regulates fluid distribution, to maintain fluid balance. However reduced albumin production and liver function cause abdominal fluid retention.
It's possible that Liver cancer and cirrhosis, which causes significant liver tissue damage, may coexist. Cirrhosis also leads to portal hypertension and liver dysfunction, increasing the risk of ascites."

At what stage of liver cancer do ascites occur?

Ascites can occur at any stage of liver cancer. It is more common in advanced stages of the disease, when cancer has spread beyond the liver or when the liver has been severely damaged. However, it is essential to note that every individual is different, and the presence or absence of ascites does not necessarily indicate the cancer stage.

Ascites can also be caused by other conditions that affect the liver, such as cirrhosis, fatty liver or portal hypertension, which can occur at any stage of liver disease. It is essential to work with a healthcare provider or liver cancer doctor to determine the cause of ascites and to develop an appropriate treatment plan.
 

Are malignant ascites in liver cancer invariably fatal?

While malignant ascites can be a sign of advanced cancer, it is not always fatal. The prognosis for an individual with malignant ascites will depend on several factors, including the underlying cause, the cancer stage, and overall health.

In some cases, treating malignant ascites may improve symptoms and extend the individual's life. Treatment options may include medications to remove excess fluid from the body, procedures to remove the fluid, and supportive care to manage symptoms and improve quality of life.
 

Does chemotherapy get rid of ascites in liver cancer?

Chemotherapy is often used to treat liver cancer, but it is not typically explicitly used to treat ascites. While chemotherapy may help shrink cancer and slow its progression, it is not usually effective at removing fluid accumulated in the abdomen.
 

How can you reduce ascites in liver cancer?

There are several ways to reduce ascites in liver cancer, depending on the underlying cause of the fluid accumulation. Some standard treatment options may include:
 

Medications: Some medications can be used to remove the excess bodily fluid. These may include diuretics, which help to increase the amount of urine produced, and other medicines that can help to reduce fluid accumulation.
 

Procedures: In some cases, a process may be necessary to remove excess fluid from the abdomen. This can be done through a paracentesis, in which a needle is inserted into the abdomen to remove the fluid.
 

Supportive care: Supportive care measures may help reduce ascites and manage symptoms. These may include a low-salt diet, elevating the head of the bed to help reduce fluid accumulation, and wearing compression stockings to help reduce swelling in the legs.
 

In some cases, a combination of treatments may be necessary to manage the condition effectively.

Can ascites come back after the treatment? Continue reading to find out.

Can ascites in liver cancer come back after being drained?

Ascites in liver cancer can come back after being drained, mainly if the underlying cause of the fluid accumulation is not addressed. Some common causes of ascites in liver cancer include cirrhosis, and portal hypertension. If these underlying conditions are not treated, there is a risk that the ascites may return.

Several factors can contribute to the recurrence of ascites in liver cancer, including the cancer stage, the effectiveness of treatment, and your overall health. 


 

How do you stop ascites in liver cancer from coming back?

There are several ways to prevent ascites in liver cancer from coming back. These may include:
 

Treating the underlying cause: It is essential to address the underlying cause of the ascites to prevent it from returning. This may involve treating cancer, managing cirrhosis, or controlling portal hypertension.
 

Taking medications as prescribed: If medications are prescribed to remove excess fluid from the body or to prevent further accumulation, it is vital to take them as directed.
 

Making lifestyle changes: Changing your diet and lifestyle may also help prevent ascites from returning. This may include reducing salt intake, avoiding alcohol, and quitting smoking.
 

Monitoring your symptoms: Pay attention to any changes in your symptoms and report them to your healthcare provider. This helps identify potential problems early on and allows for timely treatment.

It is important to work with a healthcare provider to determine the most appropriate treatment plan to manage ascites and reduce the risk of recurrence.

 

References: 

https://www.ncbi.nlm.nih.gov/ 

https://www.cancerresearchuk.org/ 

https://www.mariecurie.org.uk/ 

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Question and Answers

Hai sir, I have pain in stomech.i consult a doctor and take ct scan.The result showing is Iso hypodesnse lesion (36x33 mm) inleft lobe of liver showing intense contrast enhancement in arterial phase, persistance of contrast enhancement in portal venoys phase and appears isodence to liver in dekayed phase images posibilities :(1 )hepatic adenoma (2) flash filling haemangioma. Sir what the treatment please explain

Female | 29

It looks like you have a lesion on your liver. Hepatic adenoma or hepatic hemangioma is what this can be. Liver lesions could cause pain. Treatment will depend on the specific kind of lesion. Sometimes all that is needed is watching the lesion over time. In other cases, surgery might be required among other procedures. Make sure to follow up with your doctor so that the best plan can be made for you.

Answered on 27th May '24

Dr. Donald Babu

Dr. Donald Babu

My name is Deval and I am from Amreli. My sister in law has been diagnosed with liver cancer. Every member of our family is traumatized. Please suggest a good hospital near our location.

Treatment for liver cancer varies with the stage of disease and condition of liver. Please share her reports for appropriate guidance.

Answered on 23rd May '24

Dr. Shubham Jain

Dr. Shubham Jain

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