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  3. FDA Approved New Asthma Treatment: Breakthrough Solutions

FDA Approved New Asthma Treatment: Breakthrough Solutions

Discover groundbreaking asthma treatments. Explore innovative therapies offering improved symptom management and enhanced quality of life.

  • Pulmonologyy
By Ipshita Ghoshal 28th Nov '22 12th Aug '24
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Many people with asthma worry about losing control over their breathing every day. Asthma is chronic. It can never be cured, but simple preventive measures can go a long way toward controlling the symptoms. The symptoms of asthma vary widely from person to person. 

Some of the prevalent symptoms of asthma are as follows:

Asthma can be seen to affect people across all age groups. According to the global asthma report, asthma affects over 339 million people worldwide. The UK has the highest prevalence of asthma cases; the deaths associated with asthma have also increased by 33% from 2008 to 2020. 

was given FDA approval in December 2021. This biological maintenance drug manages all forms of severe asthma.

 Vector syringe with medical drug semi flat color vector object

More About Tezspire

Medications for asthma were already available, but the Food and Drug Administration recently approved a new asthma treatment called Tezspire. 

Tezspire is an injectable medicine. It comprises natural ingredients like sugars, proteins, and tissues. Tezspire is the first medication for asthma approved by the FDA that aims to control the severe symptoms of the disease, not the cause of the problem. This new asthma medication targets thymic stromal lymphopoietin, which causes inflammation.

The new asthma medication is an add-on option; Tezspire cannot be taken alone. It is meant to be used with other standard-of-care medications for asthma. The medications are as follows:

  • An inhaler with a medium- or high-dose of steroids to reduce airway inflammation (swelling), such as budesonide (Pulmicort)
  • An inhaler that controls the relaxation of airways, like salmeterol (Serevent).
  • Another similar kind of inhaler, like tiotropium (Spiriva Respimat).
  • An inhaler that has a combination of steroid and controller medications like budesonide/formoterol (Symbicort).


How does Tezspire work?

Tezspire works by reducing the inflammation caused by allergens. Whenever the lungs come in contact with any allergen, they release hormones that cause inflammation. Tezspire was created to stop alarmin production and reduce inflammation of the lung airways. 

Read further if you are interested in the side effects and precautions associated with Tezspire! 

Is Tezspire effective?

The new asthma treatment effectively reduces the risk associated with asthma attacks by 70% or more. During the study of the effectiveness of Tezspire, researchers found that Tezspire is beneficial for people with asthma as it considerably reduces the inflammation of the airways. 


 

Are there any side effects of Tezspire?

Like any other medication, the new asthma medication was also found to have several side effects. The side effects caused by Tezspire are:

Common side effects

Severe Side effects

  • Backache
  • Joint stiffness
  • Pin at injection point
  • Swelling at the injected site
  • Throat soreness
  • Rashes 
  • Breathing difficulty
  • Swelling in the eyes
  • Redness of eyes

What precautions are there to take while taking Tezspire?

One should take the following precautions while getting Tezspire administered:

  • Avoid using Tezspire to treat asthmatics, acute bronchospasm, acute exacerbations, or acute asthma symptoms.
  • Corticosteroid dosage must be reduced gradually after initiating the new Asthma treatment. An abrupt halt might lead to severe withdrawal symptoms.
  • Patients with Helminth infections must be treated before starting the new Asthma medication. TezSpire should be discontinued if individuals catch helminth infection after Teszspire is begun.
  • Administration of attenuated vaccines must be avoided if you are taking Tezspire.
  • Tezspire's effect on maternal health has yet to be evaluated. Hence it should be avoided by pregnant women.

After everything, if the cost of Tezspire still concerns you, you may read till the end to find out about it!


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What is the cost of Tezspire?

Tezspire was made available on the US market in January 2022. Although it won’t be available in local retail pharmacies because of the brand name. The actual cost has not been publicly disclosed, but it is anticipated to be expensive without insurance coverage.

To solve this cost problem, the manufacturers provide the advantage of the Copay Program to commercial insurance holders. This program allows you to get this new asthma treatment at minimal or zero cost. 


Many people with asthma worry about losing control over their breathing every day. Asthma is chronic. It can never be cured, but simple preventive measures can go a long way toward controlling the symptoms. The symptoms of asthma vary widely from person to person. 


References:

https://www.astrazeneca.com/

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Question and Answers

I have been getting sick with sore throat and lungs congestion for a long time now. Every month, at least two trips to the clinic with antibiotics is a must. I suspect that my asthmatic and wheezing, coughing, congestion, sinus, tonsillitis, and inflammation might br caused by mold in my home and office. How can I ask my doctor here in clinic to test my blood for the mold toxicity?

Female | 24

Mold can grow in damp areas, releasing spores that may cause illness. If you suspect mold exposure, you can ask your doctor for a blood test by saying, "I'm worried that mold at home or work may be causing my symptoms. Could we check for mold toxicity in my blood?" This test can help determine if mold is behind your health issues. In addition to treating any symptoms, it’s important to address the mold sources at home and work to improve your air quality.

Answered on 11th Nov '24

Dr. Shweta Bansal

Dr. Shweta Bansal

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