Is my irregular brown toe mark concerning?

To ensure healthy and shining skin, it is imperative to establish a consistent and appropriate skincare regimen. Use a mild face wash to cleanse; moisturizing regularly, and using sunscreen to safeguard from sunburns are also important. Using a scrub at least once/twice a week or a face mask would be nice. Thus, you remove dead skin cells to renew it

face can be made brighter and better and also improvement in the complexion. You would need topicals , and medications as well . Just medications won’t help . However you can start with antioxidants and Supplements

Your thumb may be inflicted with a blood blister. Blood blisters occur when the blood vessels under the skin are traumatized. They can be painful, and the more you compress them, the more blood will come out. For it to heal, don't scrape it off and try to save it from getting injured more. If it is causing much discomfort, cover it up with a bandage. 

Sounds more like a case of chronic fungal infection, but itching and the patches are common symptoms. Better visit the dermatologist, who will be able to tell for sure what kind of treatment is proper for this case. They will recommend you a course of special antifungal creams and oral medicine