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Male | 38

Are High MCHC, Low Hematocrit & Vitamin D Concerning?

38 year old male blood test result: high mchc and lymphocytes, low hematocrit and neutrophils. Low vitamin d. Patients brother had aml. Are these test results concerning? Should we do further testing? The reason for the blood test was bone pain on different parts on the body. Lymphocyes 52% Mchc 37 Neutrophils 38% Hematocrit 38.9% Vit d 16

1 Answer

Answered on 18th Sept '24

The increase of MCHC and lymphocytes along with the fall of hematocrit and neutrophils is a sign of some serious issues beneath. Bone pain can also be related to abnormal Vitamin D levels. Taking into consideration the family's background of AML, a decision for additional tests would be a good one to make the doubts clear. 

2 people found this helpful

Questions & Answers on "Hematology" (137)

Dear Doctor, Due to my father's high blood viscosity, suspicion of polycythemia arises, necessitating blood draws every 3 weeks to maintain appropriate levels. At 69 years old, he experiences symptoms such as skin itching, swelling, head numbness, and fatigue. Currently, his JAK2 V617F mutation showed 0.8 then 1.2%, with JAK2 exon 12 negative and EPO at 13.4. Abdominal CT and chest X-ray are normal. After a few months of phlebotomy, his levels normalized. Now, we await the bone marrow biopsy results, which do not confirm Polycythemia Vera: "Microscopic description: The bone marrow biopsy sample shows somewhat hypocellular hematopoietic parenchyma relative to age, which is terminally mature. Myeloid ratio is 2:1 with dominance of late precursors; no blast cells are noted. The number of megakaryocytes is normal with no clustering. There is no interstitial fibrosis or lymphoid infiltrate. Diagnosis: Mature, hypocellular hematopoietic parenchyma without myeloproliferative features. Cytogenetic analysis confirmed male karyotype; no clonal chromosomal abnormalities detected. Indication for examination D7510 Secondary polycythemia Note Submicroscopic rearrangements, small structural chromosomal aberrations, DNA-level differences cannot be ruled out with the method used." I am quite confused as JAK2 positivity typically suggests PV, yet the biopsy suggests otherwise, possibly indicating secondary polycythemia. Could you please clarify based on this information what you personally think is more likely, Polycythemia Vera or another secondary cause? Thank you very much for your help.

Male | 67

Your father's symptoms and test results do suggest some complexity. The presence of JAK2 mutation often points towards Polycythemia Vera (PV), but the bone marrow biopsy does not show typical myeloproliferative features, suggesting it might be secondary polycythemia instead. Consult a hematologist, specializing in blood disorders, and can provide a more accurate diagnosis and appropriate treatment plan.

 

Answered on 3rd July '24

Dr. Babita Goel

Dr. Babita Goel

I am a 7 month old baby's breastfeeding mother. I had a c section delivery but even after 7 months my body weakness is not getting better. Sometime this weakness is fine and sometimes I feel very weak. Now since last 2 3 days I am feeling dizzy, having constipation, acidity and shortness of breath and my wrist and feet are also trembling sometimes. I thought this is anemic symptoms.

Female | 25

I think perhaps you’re showing signs of a lack of iron, which often occurs after having a baby. You might feel weak, lightheaded, out of breath or have trembling hands and feet. You could also get constipated, have heartburn or feel low. Eating red meat, spinach and lentils can help because they are high in this mineral. You might also need to take an iron supplement. But talk to your doctor to make sure that’s what it is and work out a plan for getting better.

Answered on 4th June '24

Dr. Babita Goel

Dr. Babita Goel

38 year old male blood test result: high mchc and lymphocytes, low hematocrit and neutrophils. Low vitamin d. Patients brother had aml. Are these test results concerning? Should we do further testing? The reason for the blood test was bone pain on different parts on the body. Lymphocyes 52% Mchc 37 Neutrophils 38% Hematocrit 38.9% Vit d 16

Male | 38

The increase of MCHC and lymphocytes along with the fall of hematocrit and neutrophils is a sign of some serious issues beneath. Bone pain can also be related to abnormal Vitamin D levels. Taking into consideration the family's background of AML, a decision for additional tests would be a good one to make the doubts clear. 

Answered on 18th Sept '24

Dr. Babita Goel

Dr. Babita Goel

My platelet count is 5.5 lakh so it is normal or not

Male | 17

A platele­t count of 5.5 lakh is normal. These tiny cells he­lp blood clot properly. Low platelets me­an bruising easily, bleeding too much, and cuts won't stop ble­eding. High platele­ts might signal infection, inflammation, or medical issues. So, re­gular check-ups with your doctor monitor those platele­t levels. Your number looks good now. But de­finitely double-check with a doctor.

Answered on 21st Aug '24

Dr. Babita Goel

Dr. Babita Goel

I am a 26-year-old female. I have night sweats weight loss over 50 pounds hair thinning all lymph nodes have lumps and currently finding new ones. No pain in them. Double vision, headaches, constipation and diarrhea positive mono nucleus test but negative for mono, bruising and legs, bruising, and ribs, stomach and abdominal pain.

Female | 26

According to the symptoms, there may be an underlying serious illness. You should seek medical attention immediately for a correct diagnosis and treatment plan. They can mean different things such as infections, autoimmune diseases, and cancers. Do'nt wait any longer before visiting a doctor because these signs need urgent care. Your healthcare provider will do more tests to find out what is wrong with you and give you the right medication.

Answered on 28th May '24

Dr. Babita Goel

Dr. Babita Goel

I am very sick sir duwara duwara say bukhar aa raha hn and after that then urine mein blood bi aa raha hn and weekness bii What is my problem

Male | 44

Based on your explanation, you are familiar with fever and have also noticed blood in your urine. This could be a symptom of a urinary tract infection or a sign of kidney problems, both of which can also cause weakness. It would be best to consult a doctor within a few days to determine the cause and receive the appropriate care.

Answered on 23rd July '24

Dr. Babita Goel

Dr. Babita Goel

I am 38 years and married. In October, last year I went to donate blood but was told one of the test is positive for HIV. I was asked to retest after months. I did and it is still same inconclusive result. What should I do?

Male | 38

The fact that your test was inconclusive implies that it's still not clear if you are HIV positive or not. Regarding the symptoms of HIV, they are similar to fever, tiredness, and weight loss. More likely, bringing about can be unsafe sex or sharing needles. Therefore, you must see a doctor

Answered on 23rd May '24

Dr. Babita Goel

Dr. Babita Goel

Wbc-77280 per microlitre Eosinophils-63.8 per microlitre Haemoglobin-10.4 G/dL RBC-3.98 millions/cumm

Female | 51

Your blood test could indicate an issue. High WBC and Eosinophils levels, as well as low Haemoglobin and RBC counts, could mean there is an infection or inflammation present. Signs might consist of tiredness, feebleness, and generally feeling unwell. If necessary, it would be best to contact a doctor for more tests and treatment.

Answered on 6th June '24

Dr. Babita Goel

Dr. Babita Goel

Is it possible that a person have Alpha thalassemia major and still not taking any blood transfusion in entire life and now 21 yo.....or the person have only minor one

Female | 21

Alpha thalassemia major can be present in a patient who does not require blood transfusions. This form of the disorder can result in severe anemia, although it affects people differently. Some individuals may not need a transfusion at all. Signs and symptoms of alpha thalassemia may include fatigue, weakness, or paleness of skin. Treatment may consist of symptom management such as taking supplements or drugs that stimulate the production of more red blood cells within the body. Please consult a doctor for individualized advice.

Answered on 25th June '24

Dr. Babita Goel

Dr. Babita Goel

I have terrible hair fall and nose bleed followed by weight loss and weakness

Female | 16

There might be­ a few reasons for these­ issues. You could have a nutritional deficie­ncy. Or it could be stress. Or maybe anothe­r health problem. To fee­l better, eat he­althy foods. Reduce stress by re­sting more. But if this keeps happe­ning, see a doctor soon.

Answered on 23rd May '24

Dr. Babita Goel

Dr. Babita Goel

Anti hiv value 0.229 is good

Male | 19

It's great to know that your anti-HIV value is 0.229. This shows that you have a certain amount of HIV antibodies that your body has made but not many. It could mean you were infected recently or just exposed without getting sick. Keep an eye on it with frequent testing.

Answered on 10th June '24

Dr. Babita Goel

Dr. Babita Goel

After delivery, I have anemia, low pressure, dizziness, weakness. It has been a year. I am taking iron and calcium tablets continuously. Nothing is happening. What to do now. Please advise.

Female | 22

You've been feeling exhausted, lightheaded, and nauseous after childbirth. These could be signs of anemia, which means your body doesn't have enough healthy red blood cells. Even though you are on iron and calcium tablets, they may not be enough. It's important to have a blood test to see if you need a different type of iron or if something else is causing your symptoms. 

Answered on 9th Aug '24

Dr. Babita Goel

Dr. Babita Goel

Sickle cell anemia report bare main janna hai

Female | 16

Sickle ce­ll anemia is a health problem. Pe­ople with it have red blood ce­lls that are bent in a moon shape. The­ bent cells get stuck in tiny blood tube­s. This causes much hurt and low energy. It also le­ads to getting sick easily. Sickle ce­ll anemia happens because­ of a gene issue from parents. To fe­el better, pe­ople with this illness should drink lots of water, not ge­t too stressed, and see­ the doctor often for checkups.

Answered on 23rd May '24

Dr. Babita Goel

Dr. Babita Goel

Last 2 months ago mu ultrasound report spleen size is 10 cm normal.but this time my report spleen size 12.1 cm is this dangerous ?

Female | 22

Ge­tting bigger spleen from 10 cm to 12.1 cm can be­ bad sign. It can mean infections, liver proble­ms, or blood issues. You might feel pain in be­lly or feel full fast. More te­sts like blood work or scans may be nee­ded to know why. It is important to see a doctor for the right care­.

Answered on 23rd May '24

Dr. Babita Goel

Dr. Babita Goel

Spited blood from mouth Very tired Less appetite

Male | 20

You see­m to be spitting out blood from your mouth. You feel e­xtremely tired. Your appe­tite has decrease­d. These symptoms could be cause­d by different reasons. Example­s are gum problems, infections, or stomach issue­s. It's important to see a doctor. They will identify the­ cause and provide the­ appropriate treatment.

Answered on 26th July '24

Dr. Babita Goel

Dr. Babita Goel

Hi, I did Antibody hiv 1& 2 Elisa test after 30 days of exposure. Then once again I did Insti antibody 1&2 screening tes after 45 days. In both test my result was negative. Should I do further test for my assurance...please kindly suggest me

Male | 39

The tests you took at 30 and 45 days are generally accurate, but for complete peace of mind, it's best to get tested again 3 months after being exposed. This is because it takes time for the immune system to make enough antibodies that can be detected by the test. In the meantime, if you start feeling unwell with symptoms such as fever, rash, sore throat or tiredness, please tell your doctor.

Answered on 7th June '24

Dr. Babita Goel

Dr. Babita Goel

Is 3.5 mmol/l cholesterol is normal

Male | 37

When you have 3.5 mmol/l cholesterol, that is okay. Cholesterol is like fat in your blood. If your cholesterol is high, there are usually no signs. An unhealthy diet, not doing enough exercise, and a family history can cause this condition. To stay healthy with it being normal eat well and exercise regularly also if necessary take some drugs from the doctor. 

Answered on 6th June '24

Dr. Babita Goel

Dr. Babita Goel

I am suffering from fever from the past four days. Yesterday, I got my blood test checked, which included CBC Report, CRP report, and dengue and malaria test. CBC report is normal Dengue and malaria test Both negative CRP 34.1 Very high Doctor prescribed me, some medicines Relating to fever and pain killer I am feeling night sweats.

Male | 28

You are experiencing a hard time caused by that fever and high CRP level. Night sweats are one way for your body to show that it is fighting an infection. A high CRP may be a sign of inflammation in your body. Your doctor prescribing you fever medicines and painkillers is the correct way. Do not forget to rest properly, drink plenty of fluids, and listen to your doctor's orders. 

Answered on 16th Sept '24

Dr. Babita Goel

Dr. Babita Goel

I've been sick for months , my white blood cell and t cells are abnormal but primary not doing anything about it

Male | 51

Your blood tests showe­d weird white cells and T ce­lls. Those cells fight germs. So we­ird counts may mean your immune system isn't working right. Be­ing tired, sick often, and losing weight for no re­ason - those could be signs too. Visit a hematologist to get proper treatment.

Answered on 5th Sept '24

Dr. Babita Goel

Dr. Babita Goel

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