Female | 64
Why Is My Creatinine Rising in Stage 4 IGA Nephropathy?
Dr, I was diagnosed with IGA nephropathy 32 years ago. I am 64 years of age and my creatinine is 2.31 and has been hovering around that number. I have lost 124 lbs over the past year with the assistance of Zepbound. My kidneys have not improved and appear to be getting slightly worse. I run 3 miles a day and eat around 1200 calories a day never exceeding my sodium or potassium requirements. I do not have protein or blood in my urine. Please help. What is causing my creatinine to continue to rise? I am currently In Stage 4 kidney disease. Should I get an updated biopsy since my only biopsy was done in 1992. What can I do? Could the Zepbound be causing my kidneys to worsen? I drink 100 ounces of water daily.

General Physician
Answered on 8th July '24
It is concerning that your creatinine levels are rising despite your efforts. IGA nephropathy can progress slowly over time, and factors like age, diet, and medications may influence kidney function. Zepbound's impact on your kidneys should be evaluated by a specialist. I strongly advise you to consult a nephrologist for a thorough assessment and consider getting an updated biopsy to understand the current state of your kidney disease.
78 people found this helpful
Questions & Answers on "Nephrology" (129)
I'm a 21 year old female. Last year in April I had severe lower abdominal pain, went to a few doctors and turns out I had urine infection and kidney concretions, according to doctors they were very minor and they asked me to drink plenty of water to flush it out. I drank more than 3 litres of water everyday but still kinda didn't work, as I was still feeling pain on both sides of my kidneys. My stomach was upset all the time, either diarrhea or constipation. Then I consulted a homeopathic consultant, and he gave me medicines to flush out those concretions, the pain was a lot less now so I stopped his medications in November 2024 which was almost 4 months of taking homeopathic medicines. That homeopathic doctor asked me not to eat rice, spinach, tomatoes and beef. I started eating all this after I stopped his medications, in December I ate beef and the pain in my kidneys started again. Now I really don't know what to do? Is this really a kidney issue or I should get whole abdominal ultrasound to know what's wrong? And which specialist to consult for all this? My stomach doesn't feel right at all whenever I eat tomatoes and beef. My stools are stiffer and not so easy to pass. Please gimme an honest advise.
Female | 21
Given your history of kidney stones and ongoing discomfort, it's important to consult a healthcare professional for a thorough evaluation. An abdominal ultrasound can provide valuable insights. If certain foods are triggering your symptoms, keep a food diary to identify patterns. You might consider seeing a urologist for kidney-related issues or a gastroenterologist for digestive concerns. Maintaining hydration remains crucial. Remember, seeking timely medical advice can help you find the right approach to manage your health effectively.
Answered on 18th Jan '25
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Nephrologist consultation
Male | 60
Usual circumstances that necessitate a visit to a nephrologist are issues like high blood pressure or chronic urinary tract infections, which may eventually attack the kidneys. Upon your visit to the nephrologist, the doctor will examine a few tests to see how your kidneys are functioning and then give the best treatment plan to you based on the findings.
Answered on 26th Nov '24
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hi I am thapelo In 2019 december I grew something like a brick the I 've been experiencing it untli now 2024 I went to hospital 2019 they gave me respidal till now nothing has removed and then in 2020 I suspect a kidney removed because it was on the left and then with the sex organs I could feel them I dnt know what to do my life is stuck need to get to university and finish off my studies need help.
Male | 24
Several things might have caused the growth you noticed like a tumor or cyst. So you need to see a nephrologist who can properly evaluate what’s going on with your body and give a treatment plan to help ease these symptoms.
Answered on 6th June '24
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Contrast Enhanced Computed Tomography of the whole abdomen showing moderate hypatomegaly with coarse attentuation, edematous GB mild dilated portal vein,splenomegaly,diverticulituis in sigmoid colon. Crystitis. My brother suresh kumar's report has been admitted in Maharaja Agrasain Hospital, Punjabi Bagh and the doctor has recommended us for a second opinion. Kindly advise / suggest next course of action if possible.
Male | 44
Answered on 8th Aug '24
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I am having hematuria since last night. Iam diagnosed with kidney stone last year.is hematuria due to kidney stone. But I'm not experiencing any pain
Female | 20
Hematuria, or blood in the urine, can be concerning. One likely reason is a kidney issue. Even without symptoms, it’s important to find the cause. The three main reasons are infection, a moving stone, or injury. Diagnosis is usually made through tests by a healthcare provider. Treatment varies and can include increased water intake and medications. Talking to a nephrologist is best to understand what’s happening in the body.
Answered on 11th July '24
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Toilet baar baar aata hai jalan hota hai aur 1 hours me 10 to 15 times urine jaana padta hai left kidney ke 2-3mm stones hai please help me
Female | 24
You could have felt the kidney stones along with a burning/ painful situation during pee. For the larger part, kidneys produce such types of stones that are made up of water, calcium oxalate, and uric acid. Water is the best and first food to flush out these stones, so you should drink a lot of it. If the pain won't go away, visit a nephrologist and go through the advised treatments, if any.
Answered on 3rd July '24
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How many points can my creatinine increase with GFR increase after 30 days with stage 4 ckd eating low phosphorus potassium protein and sodium. I have lost some weight using peddler. In the past 30 days my blood pressure and blood sugar have been stable
Male | 76
This means less creatinine in your system. Lower creatinine is good - it shows less strain. High creatinine brings tiredness, swelling, trouble urinating. Keep tracking your progress carefully. If new worries arise, like changes in how you feel, let your nephrologist know right away.
Answered on 23rd May '24
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creatine 4.7 is normal gfr 8.5
Female | 75
A creatinine level of 4.7 and GFR of 8.5 indicate significant kidney function impairment. It's crucial to consult a nephrologist immediately for further evaluation and management. They can provide personalized advice and treatments to help preserve kidney function and maintain overall health.
Answered on 2nd July '24
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Creatinine level increase
Male | 26
An increase in creatinine levels in the blood could indicate that your kidneys are not functioning properly. Symptoms are often not present at the beginning of the disease but as it progresses you can experience tiredness and suffer nausea. Common causes are dysfunction of kidneys, dehydration, and certain medicines. To reduce creatinine levels, it is necessary to drink a lot of water, consume a healthy diet, and take medications as prescribed by a nephrologist.
Answered on 10th Sept '24
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Hi wondering is protein trace leukocytes and high ph on urine dip test a sign of kidney infection? Also has flank pain and nausea
Female | 17
When your urine test finds protein, white blood cells, and high pH with flank pain or nausea, it may mean a kidney infection. Bacteria entering the bladder usually causes these infections. Drink lots of water. Take antibiotics your doctor prescribes. See a nephrologist for a proper diagnosis and treatment plan.
Answered on 2nd Aug '24
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I will soon be seeing a urologist and possibly being referred to nephrology, my urine creatinine is 22 mmol/l, I have foamy urine, burning when I go to the toilet, and constant back pain on both sides under the ribs, what could this possibly be?
Male | 24
The foamy pee, burning when you pee, and constant back pain could mean a kidney issue. High creatinine level signifies kidney troubles. These symptoms could result from an infection, kidney stones, or a more severe kidney condition. It's crucial to visit your urologist soon to identify the cause and get proper treatment. You may need to see a nephrologist, a kidney specialist, for further evaluation and care.
Answered on 17th July '24
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Kidney stones, regular fever, chest pain, knee pain and sewling, high gass
Female | 48
It sounds like you’re experiencing a mix of concerning symptoms. Kidney stones can lead to discomfort, while episodes of fever may imply an infection. Chest discomfort could stem from various causes, and pain in your knee alongside swelling suggests inflammation. High gas may result from dietary choices or digestive issues. It's crucial to address these matters with a nephrologist who can conduct a thorough evaluation and offer tailored advice.
Answered on 19th Mar '25
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Pain in lower left side of stomach rest all parameters are normal E.g feel hungry normally, have normal bowel movement and normal urination.I was taking Cyclopam for the pain but now it's almost a month. Got my test report for Serum Creatinine level value is 0.74 mg/dlX
Male | 61
You need to get a USG of Abdomen done and a urine routine examination. For detailed information You need to consult Best Nephrologist in Thane.
Answered on 23rd May '24
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Last months i took pre medical exam for my job. Result is triglycerides 299 and stpt 52 .for that i am taking homeopathy medicine, after two days i have two practical exam and stressed a lot during exam. During those days i have seen first time that urine is foamy and till now only sometimes morning time foam is more other times only few times. What is the main cause any issue it is related to kidney? Or it is just temporary due to stress factor?
Male | 32
This could be due to several factors, like kidney issues or stress affecting the kidneys, causing temporary foamy urine. High triglycerides and STPT levels also need attention. Consulting a nephrologist will help you get the right assessment and advice.
Answered on 19th Sept '24
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Aoa, I m 43 year old male suffering from RENAL FAILURE my reports are as under . Creatinine is 19.4 Urea 218 Hb 8.4 Vomiting Abdominal pain
Male | 43
Your kidneys may not be working properly, leading to high levels of creatinine and urea in your blood. These substances should be filtered out by the kidneys but are staying in your bloodstream, causing symptoms like fatigue, low hemoglobin, vomiting, and abdominal pain. To start feeling better, you may need treatments like dialysis and medications to lower these levels. Renal failure is a serious condition, so it's important to follow a nephrologist's guidance for proper management.
Answered on 20th Aug '24
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Hello Doctor, My grandmother age is 72. She has Diabetes, BP, urinary tract infection. Recently, a mild cyst found in her kidney through CT Scan. 15 days ago, her condition went serious and we joined her In hospital. Her sugar levels were 600mg/dl. Doctors treated her and dropped her sugar levels to normal. Now, she is mentally not stable and taking full bed rest. She is unable to stand or sit on her own. She is able to recognise all of us and can eat or drink on her own. But she is very week and mentally disturbed so much. She talks unrelated. Please suggest what treatment we should take for her. Thank you doctor.
Female | 72
Your grandmother faced challenging times. Her health conditions recently caused worries. Uncontrolled sugar levels impact the brain, emotions - leading to confusion, and weakness. A kidney cyst may add stress too. Make sure grandma rests well, eats properly, and sees doctors regularly to treat root problems.
Answered on 16th Aug '24
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I am a 31 year-old male. I think I had food poisoning last friday night. I had stomach aches, vomited like 3 times but also my urine was brown-ish and what felt like my right kidney hurt. After ~14hrs of rest most of the symptoms were gone and by monday i felt as good as new and returned to eat normally. This morning I woke up with that kidney pain again. Should I go see a doctor or or will this get better by itself?
Male | 31
It sounds like you had a tough time last week with food poisoning. If you're noticing brownish urine and pain in your right kidney, it could be a sign of a kidney infection. This can return without proper treatment, so it's best to see a nephrologist for an examination and the right medication to help you recover.
Answered on 18th Sept '24
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I am 24 yrs old male I have kidney stone surgery and after dj stent removal I'm having fever for 4 days plz suggest me some advice.
Male | 24
Experiencing fever after stent removal can be a common issue, potentially indicating infection or inflammation. Other symptoms to monitor include chills, increased pain, or changes in urination. To support recovery, stay well hydrated, rest, and consider taking over-the-counter fever reducers like acetaminophen. However, it’s vital to consult your nephrologist if the fever persists, worsens, or if you have other concerning symptoms.
Answered on 13th Feb '25
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I describe below our patient problem: 1. Suggestive of left renal mass with thrombus in left vein. 2. left paraaortic lymphadenopathy. 3. Visible part of chest shows multiple soft tissue nodules in basal segments of both lung, largest one - 3.2X 2.8 cm - suggest metastasis.
Female | 36
Answered on 10th July '24
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Mera ckd stage5 hogya hai kya steemcell therapy ho sakta hai?
Male | 32
You've gotten to the fifth stage of chronic kidney disease (CKD). Your kidneys barely work at this advanced stage. Exhaustion, swelling, and chills frequently occur. Hypertension, diabetes, or other illnesses can lead to this condition. Stem cell treatment isn't typically used for CKD. Discussing treatment choices with your nephrologist is highly recommended for Stage 5 CKD management.
Answered on 11th Sept '24
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