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Female | 40

Is My Elevated Immature Granulocytes Level Cause for Concern?

Systematic increases in immature granulocytes Good morning, Firstly, I will mention that I suffer from numerous chronic inflammatory diseases, as this may be relevant. These include Ulcerative Proctitis; Atrophic Gastritis; Last year, I also underwent two cervical electrosurgery procedures due to advanced dysplasia (CIN3). (The last colposcopy and colonoscopy did not reveal any suspicious changes) For a year now, my blood morphology tests have been showing an elevated level of immature granulocytes: The latest test (May '24) showed: Immature granulocytes IG - 0.09 thousand/µl; Norm: 0-0.04 thousand/µl Immature granulocytes IG % - 1.00; Norm: 0-0.5% The rest of the blood morphology is normal, leukocytes in urine - within the norm. Previous results (April '23): Immature granulocytes IG - 0.05 thousand/µl; Norm: 0-0.04 thousand/µl Immature granulocytes IG % - 0.7; Norm: 0-0.5% (and a very slightly elevated MCV) Even older (January '23): Immature granulocytes IG - 0.04 thousand/µl; Norm: 0-0.04 thousand/µl Immature granulocytes IG % - 0.6; Norm: 0-0.5% (and a very slightly elevated MCV and basophils) There is a clear upward trend since last year. I initially thought this was due to extreme stress (CIN3, LLETZ etc). Now I am not so sure... Are these results very concerning and indicative of a cancerous process? Can chronic inflammatory states cause an increase in IG, or is it rather some kind of “acute” disease state? Could the fact that I rode a bike to the laboratory (medium and short-term physical effort) affect the increase in results? I would be very grateful for your response and advice. Best regards, J.

1 Answer

Answered on 23rd May '24

Raised levels of these are often linked to chronic inflammation similar to stress, in this case, it is important to control them initially. With the status of attempted diagnosis for specific inflammatory conditions, your previous experience, and the new procedures on the lookout for anything new, don't hesitate to let a doctor know. It would be helpful to get solid advice from your healthcare provider concerning your test results. 

64 people found this helpful

Questions & Answers on "Hematology" (169)

Hi doctor..I am Keshar shreya and my age is 24 My lactate dehydrogenase test result is 3818..what must be the reason

Female | 24

Monitoring your lactate dehydrogenase­ levels shows care for he­alth. An elevated LDH value­, like 3818, signals potential issues. This might involve­ muscles, liver, or heart. Tire­dness, muscle aches, bre­athing difficulties - these could arise­. The wise step is to consult a doctor. They'll conduct furthe­r assessments, pinpointing the root cause­.

Answered on 4th Sept '24

Dr. Babita Goel

Dr. Babita Goel

I did lft test on Friday and my globulin level is 3.70 and now Tuesday after 4 days I did again lft test and globulin level is 4 I am so scared it increasing what should I do

Male | 38

A minor rise in your globulin level in the blood profile is not usually a cause of concern. Globulin is a protein in your blood that serves as a defense against infections. The levels of this protein may at times, be affected by factors such as dehydration or infections. No need to panic if you have not noticed any change in your health or you have not developed any unusual symptoms. Consume enough water and a healthy diet of fruits and vegetables. If you observe any new symptoms or if this continues, consult with your doctor for further advice. 

Answered on 11th Oct '24

Dr. Babita Goel

Dr. Babita Goel

I am 45 yrs I am asmathic patient recently having several attack I was hospitalized with the help of oxygen I recover but I undergo some blood test in which I found out that my blood platelets are high to 424 what should I do I need your medical guidance

Female | 45

In your situation, the fact that you have asthma and that recent attacks and being in the hospital may have caused this change is possible. High platelets can be associated with easy bruising, bleeding, and fatigue. So, ensure that your asthma is under control and that you see your doctor for further evaluation and advice on medication to lower your platelet count.

Answered on 9th Oct '24

Dr. Babita Goel

Dr. Babita Goel

Spited blood from mouth Very tired Less appetite

Male | 20

You see­m to be spitting out blood from your mouth. You feel e­xtremely tired. Your appe­tite has decrease­d. These symptoms could be cause­d by different reasons. Example­s are gum problems, infections, or stomach issue­s. It's important to see a doctor. They will identify the­ cause and provide the­ appropriate treatment.

Answered on 26th July '24

Dr. Babita Goel

Dr. Babita Goel

Hi There , I am a 32 year female old, I recently did a full blood count test and another test for my kidneys to check for any abnormalities and everything came back positive , however lately my hands feel kinda full and painful, they feel hard when i open and close them , they do look swollen but not too much, especially when i wake up every morning, when im sleeping i can feel the blood flowing to my hands

Female | 32

You might be having the symptoms of a condition known as carpal tunnel syndrome. This can be a result of the nerve in your wrist being compressed, which in turn, leads to pain, swelling, and numbness in your hands. To help with the symptoms, you can try wearing a wrist splint at night, doing hand exercises, and taking breaks from activities that may worsen the pain. If the symptoms carry on for some time, it's best to seek further help from a hematologist.

Answered on 23rd Oct '24

Dr. Babita Goel

Dr. Babita Goel

I am 23 year old female.. I have continuous bruise on my leg and arm without hitting last 3 year.. I didn't eat any medicine.. so what should I do now?

Female | 23

An occurrence of bruising without any previous history of trauma or injury is a condition that needs attention. You are doing right not to take medicines right away. Bruising without an obvious cause could be due to low platelet count, clotting disorders, or Vitamin deficiencies. The optimal way to find out is through an in-person appointment with a specialist who will draw blood in a lab to diagnose the disease. 

Answered on 23rd May '24

Dr. Babita Goel

Dr. Babita Goel

I had a long time bleeding what could be the cause

Female | 21

Pills and other stuff can also cause lots of blee­ding. Heavy periods, fee­ling sleepy, and head spinning around are­ signs that show there is something wrong. It is important to te­ll a doctor if bleeding happens for too long so the­y can help fix the problem and make­ you feel bette­r.

Answered on 23rd May '24

Dr. Babita Goel

Dr. Babita Goel

10:48 Investigation Observed Values HAEMATOLOGY Units Blological Ref. Interval Complete Blood Count Haemoglobin 12.2 Total Leucocyte Count (TLC) 14700 gm/dL cells/mm² 12-16.5 Differential % Leucocyte Counts: Granulocytes 71.6 % 40-75 Lymphocytes 23.1 % 20-45 Mid Cell 5.3 % 1-6 Platelet Count 2.07 Lac cells/mm² 150000-400000 LPCR 22.2 % 13.0-43.0 MPV 9.1 fl. 1.47-7.4 PDW 12.1 % 10.0-17.0 PCT 0.19 & 0.15-0.62 Total RBCs MCV (Mean Cell Volume) 4.17 Million cells/uL 4-4.5 72.7 fl. 80-100 MCH (Mean Corpus. Haemoglobin) 29.4 pg 27-32 MCHC (Mean Corpus. Hb Conc.) 40.4 g/dl 32-35 HCT (hematocrit) 30.3 RDWA RDWR 40.4 11 % fL 36-46 37.0-54.0 % 11.5-14.5

Female | 48

According to the blood test results you provided, the total white blood cell (TLC) count is above the norm, which may be indicative of an infection or inflammation in the body. High TLC may come with symptoms like fever, fatigue, and coolness of the body. To deal with this problem, it is necessary to find the primary cause of the increased TLC level by conducting more tests and getting a doctor's opinion for suitable treatment.

Answered on 8th Aug '24

Dr. Babita Goel

Dr. Babita Goel

Intensive work up for HIV should be done in patients with progressively decreasing CD4 count (<300) and CD4:CD8 ratio.

Male | 13

Someone­'s CD4 count below 300 and off-kilter CD4:CD8 ratio signal immune woe­s, perhaps from HIV. HIV weakens immunity. At first, HIV infe­ction shows no symptoms but later allows easy infections. Early te­sting and treatment promote he­alth.

Answered on 11th Sept '24

Dr. Babita Goel

Dr. Babita Goel

Contrast Enhanced Computed Tomography of the whole abdomen showing moderate hypatomegaly with coarse attentuation, edematous GB mild dilated portal vein,splenomegaly,diverticulituis in sigmoid colon. Crystitis. My brother suresh kumar's report has been admitted in Maharaja Agrasain Hospital, Punjabi Bagh and the doctor has recommended us for a second opinion. Kindly advise / suggest next course of action if possible.

Male | 44

WhatsApp the report to me

Answered on 8th Aug '24

Dr. Pallab Haldar

Dr. Pallab Haldar

I'm 23 years female got pap test last month and I have a doubt that speculum is not sterlized will I get hiv from this way .speculum is not used for 2 hours before the pap test

Female | 23

The risk of HIV transmission from a speculum is extremely low. The risk is even lower if the speculum was not used for more than two hours prior to the Pap test. If you are still concerned, please speak with your healthcare provider.

Answered on 23rd May '24

Dr. Babita Goel

Dr. Babita Goel

mesenteric lymphadenopathy Lymph nodes size 19mm

Female | 20

mesenteric lymphadenopathy is 19 mm in size when the lymph nodes in your stomach get swollen. It may be caused by infections, cancers or inflammatory diseases. The symptoms include belly pain, bloating, and fever. The doctor will find what is causing it and tell you what to do next. 

Answered on 14th June '24

Dr. Babita Goel

Dr. Babita Goel

Is it normal to feel weak and loss of appetite after a week of getting treatment of Bilharzia.

Male | 34

After tre­atment for Bilharzia, feeling we­ak and losing appetite is common. Medicine­s used can cause these­ side effects. We­akness happens as the body fights infe­ction. Drink lots of water and eat healthy foods, de­spite no appetite. If symptoms worse­n or persist, inform your healthcare provide­r.

Answered on 19th July '24

Dr. Babita Goel

Dr. Babita Goel

I'm 21 years old women I've a question today i had a CBC 1 blood test and 3 days back i smoked cigarette will my doctor be able to make out by seeing my blood reports that i smoked ?

Female | 21

Cigarette smoking tends to impact the results of CBC blood tests but they don’t directly reveal it. By increasing your white blood cell count, smoking may indicate signs of inflammation or an infection to a physician. Tell truthfully about your smoking habits when asked by healthcare practitioners so that they can provide appropriate treatment for you.

Answered on 11th June '24

Dr. Babita Goel

Dr. Babita Goel

I have had 5 bosebleeds the last 24 hours, which is not like me at all. What should i do? I was at the doctors a month ago and everything other than my vitamin d and folate levels were good. I have been dizzy and very tired lately

Female | 16

Many factors can cause nose­bleeds. Dry air and allergie­s may play a role. High blood pressure too. Ye­t, dizziness, and fatigue raise conce­rns. Underlying issues like ane­mia or blood clotting problems could exist. With repe­ated noseblee­ds over 24 hours, seeking me­dical advice soon becomes crucial. Your doctor can evaluate­ properly. 

Answered on 3rd Sept '24

Dr. Babita Goel

Dr. Babita Goel

My hemoglobin report 8.2 and my esr 125

Male | 37

According to your test results, your hemoglobin level is low, which can cause symptoms like feeling tired and weak. The high ESR number could mean that your body is inflamed. From simple ones, such as anemia, to complex ones, such as infection-are sorts of them. If you want to take your hemoglobin to the right levels, you may have to take in more iron-rich foods by way of diet. Plus, do not forget that the root cause of inflammation is there and lower your ESR count. To improve your hemoglobin, you may need to eat more iron-rich foods, and addressing the underlying cause of inflammation can help lower your ESR level.

Answered on 14th June '24

Dr. Babita Goel

Dr. Babita Goel

I have lower abdominal pain for 5days. I have done my full boy test. But there is many problems like hemoglobin low, ESR high, creatinine low,bun low, vitamin d 25 hydroxy low. Now what should I do ?

Female | 14

The pain in your lower abdomen, along with low hemoglobin and high ESR levels, along with decreased creatinine clearance and reduced UV-B irradiation exposure, can be associated with various health conditions. These signs may indicate issues like anemia of chronic disease, inflammation, kidney malfunction, or vitamin D deficiency. It’s important to consult a doctor for a thorough check-up and personalized treatment plan.

Answered on 5th July '24

Dr. Babita Goel

Dr. Babita Goel

I am suffering from fever from the past four days. Yesterday, I got my blood test checked, which included CBC Report, CRP report, and dengue and malaria test. CBC report is normal Dengue and malaria test Both negative CRP 34.1 Very high Doctor prescribed me, some medicines Relating to fever and pain killer I am feeling night sweats.

Male | 28

You are experiencing a hard time caused by that fever and high CRP level. Night sweats are one way for your body to show that it is fighting an infection. A high CRP may be a sign of inflammation in your body. Your doctor prescribing you fever medicines and painkillers is the correct way. Do not forget to rest properly, drink plenty of fluids, and listen to your doctor's orders. 

Answered on 16th Sept '24

Dr. Babita Goel

Dr. Babita Goel

My wife is suffering with low hemoglobin, RBC , WBC & patlets count gone on decreasing .She has sufferd with viral fever for 15 days, viral fever came to normal but counts were not increasing.she has treated 20 days in KIMS, hyderabad hospital. Kims doctors told that after few days gradually counts will increase. What is her problem upto now doctors did not diagnosis, Two or three days doctors are transmitting sdp and prbc and WBC injections.I'm taken second opinion he told that there is a problem in bone marrow.without daignoses if we take bone marrow treatment does patient get any side effects.she is suffering from legs pain and swalling in legs aslo and she is becoming weak. Please what is her problem give me the clarity

Female | 36

she needs detailed hematological evaluation.and depending on all the reports, diagnosis can be made 

Answered on 23rd May '24

Dr. Soumya Poduval

I have tested my iron deficiency today and it was low so can i take "Astyfer-Z hematinic with amino acids vitamins and zinc liquid syrup" Which my father bought from a medical store and asked to take 10ml per day , is it okey to take it

Male | 21

Iron deficiency can cause you to have low energy, feel weak, and may lead to malfunctioning of the human body. This is due to the insufficient intake of iron-rich foods and blood loss. Aspyfer-Z syrup boosts iron levels in your body and contains iron, amino acids, B-group vitamins, and zinc. It can be done under the supervision of your father but ensure you get a follow-up guide from a doctor.

Answered on 20th Aug '24

Dr. Babita Goel

Dr. Babita Goel

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