Get answers for your health queries from top Doctors for FREE!

100% Privacy Protection

100% Privacy Protection

We maintain your privacy and data confidentiality.

Verified Doctors

Verified Doctors

All Doctors go through a stringent verification process.

Quick Response

Quick Response

All Doctors go through a stringent verification process.

Reduce Clinic Visits

Reduce Clinic Visits

Save your time and money from the hassle of visits.

Ask Free Question

  1. Home >
  2. Blogs >
  3. FDA Approved New Treatment for Bile Duct Cancer 2022
  • Cancer

FDA Approved New Treatment for Bile Duct Cancer 2022

By Rahul Chauhan| Last Updated at: 27th Mar '24| 16 Min Read

Bile ducts are slim tubes that carry a liquid called bile from your liver to the gallbladder and the small intestine. When cancer cells start forming in the bile ducts and destroying healthy cells, such a condition is called cholangiocarcinoma or bile duct cancer.

Bile duct cancer is a rare kind of cancer. It accounts for 10% to 20% of all liver cancers. Bile duct cancer might be rare. However, it is one of the most threatening types of cancer, responsible for many deaths worldwide.

Hence, it is necessary to get proper treatment in time.

Bile duct cancer may not have a cure, but it is possible to control the disease with timely and effective treatment. Lytgobi is one such treatment. We have covered this new treatment for bile duct cancer in depth.

More About New Treatment for Bile Duct Cancer

Lytgobi is a prescription drug used to treat bile duct cancer (intrahepatic cholangiocarcinoma) in adults with a specific type of abnormal FGFR2 gene.

Lytgobi was developed to treat bile duct cancer that has spread or cannot be eliminated by surgery. Lytgobi is a fibroblast growth factor receptor (FGFR) inhibitor that stops cancer cells from growing and multiplying.

It is preferred in patients who have already received previous treatment and whose tumor has a particularly unusual FGFR2 gene.

Oncologists will test your cancer for a specific abnormal FGFR2 gene and ensure that Lytgobi is right for you.

It has yet to be determined whether or not this medication is safe and effective in children.

 

What are its Side Effects?

Like any other treatment, this latest bile duct cancer treatment has adverse effects. 

 

Regardless of how meager, you should know them!

The following are some of the known side effects of Lytgobi:

Note: There might be more side effects yet to be identified.

You should know many more before starting the new bile duct cancer treatment.

We have them curated. 

 

So please pay attention!


Considerations for New Treatment for Bile Duct Cancer:

  • Lytgobi is not suggested for pregnant women. It can harm your unborn baby or cause miscarriage. 
  • It is suggested not to breastfeed during and for one week after the treatment.
  • It would help if you did not eat or drink grapefruit products during your treatment.
  • If you vomit after taking one dose, do not take another. Administer regular dose the next day at the usual time.
  • Tell your doctor immediately if you see any changes in your vision during treatment, such as blurred vision, flashes of light, or seeing black spots.
  • It is suggested to take eye gels or artificial tears during treatment to prevent or treat dry eyes.
  • Your doctor may prescribe changes in your diet, phosphate-lowering therapy, or change, interrupt, or stop treatment if needed.
  • Tell your healthcare provider immediately if you develop muscle cramps, numbness, or tingling around your mouth.

References:

https://www.prnewswire.com/news-releases/fda-approves-taihos-lytgobi-futibatinib-tablets-for-previously-treated-unresectable-locally-advanced-or-metastatic-intrahepatic-cholangiocarcinoma-301638254.html

https://www.clinicaltrialsarena.com/comment/approval-lytgobi-cholangiocarcinoma/

https://www.curetoday.com/view/fda-approves-lytgobi-for-advanced-cholangiocarcinoma

Related Blogs

Question and Answers

. Heterogeneous Soft Tissue Nodule in the Right Lower Lobe (RLL) Size: 14 x 8 mm This nodule is described as heterogeneously enhancing, which suggests it may have varying levels of blood flow or different tissue densities within it. This could be indicative of a tumor. 2. Air Space Opacification in the Right Upper Lobe (RUL) Finding: There is patchy air space opacification with interlobular septal thickening in the posterior segment of RUL. This could represent infection, inflammation, or more concerningly, metastatic disease or lung cancer causing these changes. 3. Left-sided Pleural Effusion and Subsegmental Atelectasis Pleural Effusion: Mild left-sided pleural effusion is noted. Pleural effusion can occur in the context of metastatic disease or cancer. Atelectasis: This refers to partial lung collapse, which may occur when there is a mass obstructing the airflow or due to pleural fluid. 4. Enlarged Mediastinal and Hilar Lymph Nodes Lymphadenopathy: There are multiple enlarged and necrotic lymph nodes, most notably in the right hilar region, with the largest measuring 35 x 25 mm. Enlargement and necrosis of lymph nodes can be a sign of metastatic spread. The presence of enlarged lymph nodes in the mediastinum and hilum is typical of malignancy spreading beyond the primary lung site. 5. Liver Lesion Size: 14 x 13 mm lesion in the right hepatic lobe, which is well-defined and peripherally enhancing. A hypodense lesion could indicate a metastatic tumor, especially since it shows peripheral enhancement, a characteristic of some types of metastases. 6. Skeletal Lesions Multiple Lesions: There are mixed lytic and sclerotic bony lesions, some with soft tissue components. These lesions involve the vertebrae, ribs, glenoids, sternum, sacral ala, iliac bones, and femur. Soft Tissue Components: Some of the lesions, such as those in the ribs and iliac bones, have a soft tissue component, which suggests more advanced involvement, possibly indicating metastases. 7. Other Findings: No signs of emphysema, bronchiectasis, or pneumothorax were noted, which is reassuring as it reduces the likelihood of certain types of lung diseases. The liver, spleen, pancreas, kidneys, urinary bladder, and prostate all appear normal on imaging, which helps to rule out major issues in these organs. Impression: The findings of a heterogeneously enhancing solitary pulmonary nodule in the right lung, with associated hilar and mediastinal lymphadenopathy, along with a hepatic lesion and extensive skeletal involvement (with mixed lytic and sclerotic lesions), strongly raise concern for metastatic disease, most likely originating from the lung. The primary lung cancer is a potential consideration, though other primary sites are also possible. Next Steps: Histopathological correlation: This means a biopsy or tissue sample should be taken from one of the lesions (pulmonary, hepatic, or bone) to confirm whether the lesions are malignant and, if so, to identify the type of cancer. This will help determine the best course of treatment. The overall picture suggests a metastatic malignancy, likely of pulmonary origin, but further investigations and biopsy are essential to establish a definitive diagnosis and treatment plan.

Male | 58

Answered on 8th Mar '25

Read answer

Cancer Hospitals In Other Cities

Top Related Speciality Doctors In Other Cities

Cost Of Related Treatments In Country

Consult