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Female | 64

Why is my Creatinine Rising with IGA Nephropathy?

I am a 64 year old female who was diagnosed with IGA nephropathy in 1992. I am now Stage 4. My creatinine hovers around 2.38 and my GFR is 23. I do not have protein spillage or blood in my urine. I have lost 124 lbs over the last 12 months with the assistance of Zepbound? Please help me understand what is causing my Creatinine to continue to rise? Could the Zepbound be causing this? I eat 1200 calories a day and stay within my sodium and potassium goals. I run 3 miles a day. But my kidneys are continuing to worsen. Please help me understand what else I can do. What is causing my creatinine to continue to rise? Should I get another kidney biopsy since my last biopsy was 32 years ago? Thank you so much for your help.

1 Answer

Answered on 7th June '24

Considering your circumstance with IGA nephropathy, it is usual that creatinine levels may increase as kidney functions get worse. Also, rapid weight loss may affect kidney function. It is good that you are committed to eating right and exercising, but running 3 miles every day could strain your kidneys more. You should talk about these worries with a nephrologist. A further kidney biopsy might be able to tell what is happening to your kidneys now.

98 people found this helpful

Questions & Answers on "Nephrologyy" (101)

Hello sir/mam, i have pain over left side abdomen from last 3 days, severe in morning and subsides as the day passes, fever, no burning sensation. Xray KUB is normal, Usg shows small renal cortical cyst and tiny calcific foci, features suggestive of pyelonephritis. Dr. gave me IV ceftriaxone for 10 days. Pain is still there after 2 days of treatment.What should i do for the cortical cyst ?

Male | 25

You have been experiencing pain in your left abdomen and have undergone treatment for pyelonephritis. An imaging scan showed that a small renal cyst slightly off the cortex in the kidney is the possible cause of some of your symptoms. Briefly, such cysts are usually benign and do not require treatment unless they grow or cause symptoms. In your situation, please continue to receive the necessary treatment for the infection, and they will also check the cyst to be sure it is not causing any inconvenience. 

Answered on 8th Aug '24

Dr. Babita Goel

Dr. Babita Goel

Dialysis patient in one years

Male | 34

For a dialysis patient unwell for a year, it’s important to stay alert to symptoms like fatigue, swelling, or difficulty breathing, as these may indicate the dialysis isn’t working effectively. This can happen due to missed treatments, not taking medications, or poor diet choices. It's essential to consult the dialysis team to address these issues and adjust the treatment plan for better health.

Answered on 21st Oct '24

Dr. Babita Goel

Dr. Babita Goel

I have removed 9.5mm ureteral stone 3 months ago and doctor advised to do a songography usg abdomen pelvis after 3 months. i was diagnosed with 1 stone in Right mid calyx - 4mm 1 stone in left mid calyx - 4.2mm 1 stone in left lower calyx - 3.4mm

Male | 34

So you need to workup the cause for stone formation. The stone can be removed multiple times still you need to treat the cause it is happening.

Answered on 23rd May '24

Dr. Abhishek Shah

Firstly, approximately 20 years ago, I experienced a significant shoulder impact while playing football, resulting in a sprain that extends from my neck to the back of my shoulder. Whenever I engage in physical activity, particularly on the injured right shoulder side, I feel a burning sensation accompanied by heat. Additionally, I've noticed that my right hip appears elevated since the injury. In a previous scan, I discovered a left-sided disc prolapse. Moreover, I occasionally experience sprains in the middle of my back. I have not been taking any medications for this issue as previous doctors have been unable to identify the problem. I am concerned about the long-term implications and would greatly appreciate your expertise in evaluating and providing guidance on the appropriate course of action. Are there any specific tests or examinations that you recommend to better understand the underlying causes and potential treatment options for my shoulder, hip, and back issues? Furthermore, I recently discovered that I have kidney stones in both of my kidneys. I do not have diabetes or high blood pressure, and I am not diagnosed with arthritis. Additionally, I have been informed that I have elevated uric acid levels. Considering these multiple health concerns, I am wondering if blood tests or any other diagnostic tests would be beneficial in identifying any potential connections between these issues and guiding the most appropriate treatment plan.

Male | 44

To address your musculoskeletal concerns consult an orthopedic specialist. They would recommend imaging studies, physical therapy, and medications as needed. For your kidney stones and elevated uric acid, seek guidance from a urologist nearest to you or a nephrologist who can perform diagnostic tests. I suggest to follow certain dietary changes, and monitor your kidney health. Open communication with your specialists for a tailored treatment plan for your multiple health concerns.

Answered on 23rd May '24

Dr. Neeta Verma

Dr. Neeta Verma

What type of disease is this symptoms, 1.swollen legs and hands 2.internal joints pain 3.feet and finger pain 4.smelly urine when peeing during swollen legs

Female | 27

Swelling of the legs and hands, painful joints inside your body, and also hurting feet and fingers can be caused by a condition called Rheumatoid Arthritis. The immune system gets confused and starts to attack the joints which are the reasons for the pain and inflammation. Smelly urine during swollen legs might be a sign of kidney problems. Enough water intake and medication are the ways to manage symptoms.

Answered on 23rd Sept '24

Dr. Babita Goel

Dr. Babita Goel

30 year old, creatine and urea level high, diarrheas, from past 4 days. Back ache.

Male | 30

 you need to visit emergency department if your bp is more than 180/100 and having symptoms like headache for properly evaluation and management of your condition. This could be hypertensive emergency and needs immediate ecg and bp lowering medication to avoid possible complications.

Answered on 23rd May '24

Dr. Ramit Sambyal

Dr. Ramit Sambyal

Right nephrolithiasis. - Findings s/o clot in POD & right adhexa and moderate hemoperitoneom. Wo falnt UPT eve status possibility of ruptured right adnexal estopie needs to be considered unless proven othervise. DVD rupture hemorthagic cyst. Minimal eterogenous collection within endoeterial cavity likely blood clot

Female | 35

The symptoms are similar to a clot that is apparently located in the right lower stomach according to your description. These are a variety of factors such as a burst cyst or it's possible that the right ovary is affected. The common signs that may occur are pain, bloating, or abnormal bleeding. It is necessary to perform additional tests for identification and then plan the appropriate treatment accordingly.

Answered on 23rd May '24

Dr. Babita Goel

Dr. Babita Goel

Kidney stone Left right both

Male | 22

Kidney stones might develop on one side of the body or both. They are similar to small stones that grow in a person's kidney. Signs include urine containing blood, having a problem urinating, and pain in the back or side. Causes may result from not drinking enough water and eating too much salt. To cure this condition, one may need to take a lot of fluid or use particular drugs; in some cases, an operation might be necessary to remove the stones.

Answered on 8th June '24

Dr. Babita Goel

Dr. Babita Goel

Şu anda 20 yaşındayım yeni biyopsi oldum sonucuma bakarmısınızIKLAMA: 7yaşında nefrotik sendrom tanısı alan ve tedavi gören olgu, albumin düşüklüğü sebebi ile biyopsi alınma kliniği bildirilen olguya ait HE detayda, 20 adet glomerül izlenmiş olup, 2 glomerülde global skleroz izlenmiştir. Diğer glomerüller irili ufaklı çaplarda olup, Bowman aralıkları açık olarak gözlendi. Glomerüler bazal membranlarda hafif kalınlaşma bazı glomerüllerde mevcuttu. Ancak tüm glomerüllerde mezengial hücre artışı-matriks artışı gibi bulgular izlenmedi. Glomerüler alanda izlenen bulgular spesifik olarak izlenmezken,interstisyel damarlardan (orta çaplı damarlarda) bir tanesinde duvar kalınlaşması, lümen daralması gibi vasküler basınç değişiklikleri lehine yorumlanabilecek bulgular izlenmiştir. Detayda ilave olarak interstisyel fibrozis (%20-25) iken; interstisyel alanda köpüksü histiositler ve lenfoplazmositlerin de eşlik ettiği ksantogranülomatöz pyelonefrit morfolojisi izlendi.Tubuler alanda patoloji izlenmedi. Sayfa 1\ 2

Dişi | 20

Answered on 12th Aug '24

Dr. Babita Goel

Dr. Babita Goel

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