Male | 67
What is the recommended treatment after colon cancer surgery with liver metastasis and positive HER2 score?
My uncle 67 years old had a surgery to remove colon cancer and one liver metastasis, the tumor tests are : mismatch repair proficient, her 2 +ve score 3+ , braf for v600e negative, what is next?

Oncologist
Answered on 23rd May '24
After the surgical removal of colon cancer and a liver metastasis, the next steps may involve targeted therapy, given the HER2-positive status, possibly with drugs like trastuzumab. Since the BRAF V600E mutation is negative, certain chemotherapy options may be effective. Your uncle's oncologist will tailor a treatment plan based on these findings, incorporating adjuvant chemotherapy and possibly targeted therapies. Regular follow-ups and open communication with the healthcare team will be essential for ongoing care and monitoring his response to treatment.
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Questions & Answers on "Cancer" (367)
My grandfather suffering from Esophageal cancer and his age is 68 years, so what is the possible treatment for this, and which is the best caring hospital in Chennai?
The treatment of esophageal cancer depends upon several factors stage, fitness level, and type. Treatment modalities can be surgical intervention, chemotherapy, and/ or radiation therapy. In Chennai, prominent hospitals such as Apollo Hospitals, MIOT International, or Cancer Institute (WIA) are options for advanced treatment. Consulting an oncologist is essential to evaluate your grandfather’s condition and determine the optimal treatment plan that addresses his requirements.
Answered on 23rd May '24
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. Heterogeneous Soft Tissue Nodule in the Right Lower Lobe (RLL) Size: 14 x 8 mm This nodule is described as heterogeneously enhancing, which suggests it may have varying levels of blood flow or different tissue densities within it. This could be indicative of a tumor. 2. Air Space Opacification in the Right Upper Lobe (RUL) Finding: There is patchy air space opacification with interlobular septal thickening in the posterior segment of RUL. This could represent infection, inflammation, or more concerningly, metastatic disease or lung cancer causing these changes. 3. Left-sided Pleural Effusion and Subsegmental Atelectasis Pleural Effusion: Mild left-sided pleural effusion is noted. Pleural effusion can occur in the context of metastatic disease or cancer. Atelectasis: This refers to partial lung collapse, which may occur when there is a mass obstructing the airflow or due to pleural fluid. 4. Enlarged Mediastinal and Hilar Lymph Nodes Lymphadenopathy: There are multiple enlarged and necrotic lymph nodes, most notably in the right hilar region, with the largest measuring 35 x 25 mm. Enlargement and necrosis of lymph nodes can be a sign of metastatic spread. The presence of enlarged lymph nodes in the mediastinum and hilum is typical of malignancy spreading beyond the primary lung site. 5. Liver Lesion Size: 14 x 13 mm lesion in the right hepatic lobe, which is well-defined and peripherally enhancing. A hypodense lesion could indicate a metastatic tumor, especially since it shows peripheral enhancement, a characteristic of some types of metastases. 6. Skeletal Lesions Multiple Lesions: There are mixed lytic and sclerotic bony lesions, some with soft tissue components. These lesions involve the vertebrae, ribs, glenoids, sternum, sacral ala, iliac bones, and femur. Soft Tissue Components: Some of the lesions, such as those in the ribs and iliac bones, have a soft tissue component, which suggests more advanced involvement, possibly indicating metastases. 7. Other Findings: No signs of emphysema, bronchiectasis, or pneumothorax were noted, which is reassuring as it reduces the likelihood of certain types of lung diseases. The liver, spleen, pancreas, kidneys, urinary bladder, and prostate all appear normal on imaging, which helps to rule out major issues in these organs. Impression: The findings of a heterogeneously enhancing solitary pulmonary nodule in the right lung, with associated hilar and mediastinal lymphadenopathy, along with a hepatic lesion and extensive skeletal involvement (with mixed lytic and sclerotic lesions), strongly raise concern for metastatic disease, most likely originating from the lung. The primary lung cancer is a potential consideration, though other primary sites are also possible. Next Steps: Histopathological correlation: This means a biopsy or tissue sample should be taken from one of the lesions (pulmonary, hepatic, or bone) to confirm whether the lesions are malignant and, if so, to identify the type of cancer. This will help determine the best course of treatment. The overall picture suggests a metastatic malignancy, likely of pulmonary origin, but further investigations and biopsy are essential to establish a definitive diagnosis and treatment plan.
Male | 58
The imaging results indicate several concerning findings, including a nodule in the lung, fluid around the lungs, and enlarged lymph nodes, which could suggest a more significant issue, possibly a spread of cancer. While these findings can be alarming, they do require careful evaluation. I recommend consulting your oncologist for a thorough discussion and potential biopsy, which is crucial for accurate diagnosis and treatment options.
Answered on 8th Mar '25
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Hello im 22 years old girl....I have one side nipple (tit) dryness problem .... why it's so?
Female | 22
Difficult to answer this question without examination and history, though broadly speaking sinister cause like cancer is rare in such young age, benign skin problems are more common. However it'll be advisable to visit a surgeon for evaluation..
Answered on 23rd May '24
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Chest main ganth hai doctor ne check kiya to usmein cancer bataya
Male | 62
Answered on 23rd May '24
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Hi, I am Anil Choudhary, Male, 58 yrs. It is a case of Oral Cancer: CA RT BM+ LEFT BM SUSPICIOUS VERRUCOUS LESION. The doctors have suggested surgeries on both left and right side. Other Ailments: Diabetic since 15yrs. (On Gluconorm PG2 and Lantus 10 units) What would be the approx operation estimate in Kokilaben Hospital Mumbai? What would be the ideal operation cost considering there will be free flap on both the sides without involving any bone reconstruction?
Male | 58
Answered on 23rd May '24
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Hello, I'm 48 yrs old male, diagnosed with AML in August 2020, underwent intense chemo. Achieved remission after cycle1. After 4 cycles of chemo in april 2021, I was advised to take preventive chemo thats milder (Azacitidine for 12 cycles). This chemo started in May 2021 until Nov 2022. Now I have achieved complete remission & stopped all treatment. what are my chances here, is there a likelihood of relapse, if yes should I take any preventive steps like ayurveda etc. I dont have prior history of smoking or drinking, have maintained healthy diet all along
Male | 48
Remission from treatment is wonderful news. Your relapse chances vary but maintaining a healthy lifestyle remains vital. AML relapse risk exists, as it's a complex cancer. Ayurvedic therapies support wellbeing, but regular medical follow-ups catch relapses early. Keep doing what you're doing, and stay connected with your care team.
Answered on 1st Aug '24
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Ive always had discharge for as long as I can remember and at my 8 week postpartum checkup the doctor checked me but said it wasn’t alarming because it’s not bothering me. I am currently 4 months postpartum and noticed I was getting discharge that had a slight odour and the discharge left rashes between my thighs and it got to the point I couldn’t wear underwear because the discharge would get more and I keep getting rashes. I noticed it getting a little bit better when I stopped wearing underwear the smell was still slightly fishy but not too terrible like before but recently after sexual intercourse I bled a little. Now google says it’s either the C word or some infection. I’m aware I should go doctor right away but I’m just not able to do so , my last two screenings for cervical cancer with my Pap smear came negative it was in 2018 and 2021. What’s the reason I bled?
Female | 27
Postpartum, it is normal to discharge but rashes and odor can prove an infection. Sex-related bleeding is not normal and may indicate a problem. This is why it’s important to go and see a doctor so that they can rule out any serious conditions. Cervical cancer screenings are also significant, but they do not detect all problems. If you are experiencing symptoms, do not waste time before seeing a doctor.
Answered on 23rd May '24
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good evening, i'm 69 years Male, i got cancer. I'm looking for best oncologist surgery doctor Tata memorial hospital @ Mumbai.
Male | 69
It's important to seek expert care at renowned institutions like Tata Memorial Hospital in Mumbai, known for its outstanding oncologists and surgical teams. Symptoms can vary but often include unexplained weight loss, fatigue, or unusual changes in health. Causes can range from genetic factors to environmental influences. I recommend scheduling a consultation with a oncologist there. They will assess your specific situation and outline personalized treatment options.
Answered on 20th Feb '25
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I had pain in my armpit without lumps and even body aches, fatigue, bloating, reduced appetite and breathlessness occasionally. So I consulted general physician, he checked but no lumps found and he said due to panic regarding this lump I was getting all symptoms. But he suggested for thyroid and usg whole abdomen. Yesterday the reports came in which stated only cysts were found and nothing serious. But two days ago I observed a small pea size lump on my neck and stinging pain radiating in my body and hoarness. And yesterday I observed a swollen abdomen with pain What should I do. I fear it's cancer. I observed all this within a week of time
Female | 23
It’s good that you consulted a general physician and got tests done. Since you’ve now noticed a lump in your neck, hoarseness, and other symptoms like body pain and abdominal swelling, I recommend visiting an endocrinologist or oncologist. They are specialists in thyroid and other conditions that might need further examination. It’s important not to jump to conclusions but to get proper advice from a specialist for peace of mind and accurate diagnosis.
Answered on 29th Oct '24
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I've experienced dark blood in my feces and soreness under my right rib cage for the past three weeks. I'm also losing my appetite and becoming incredibly bloated and uncomfortable anytime I eat anything, even if it's only a small amount. I was diagnosed with pancreas cancer after undergoing numerous tests. But my doctor is not telling me anything clearly, he is not answering my queries. which makes me more anxious. Please suggest something to me. I want to go for a second opinion. I live in Patna.
You need to consult a oncologist and show him all the reports for proper treatment.
Answered on 23rd May '24
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Can you cure colon cancer stage 4
Female | 37
Curing colon cancer at stage 4 is difficult but it is not impossible. The primary treatment for stage 4 colon cancer is chemotherapy, which aims to shrink the cancer or in some cases radiation therapy is used. Consult an oncologist who can recommend a proper treatment plan for you.
Answered on 23rd May '24
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My father has diagnosed with liver cancer after many examinations. Since he lives in Eritrea (Africa), which hospital would you recommend me for best Liver Cancer treatment? What are the services provided to international patients?
Answered on 23rd May '24
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Does Colon cancer affect a person's digestive system? How bad does it get as colon cancer progresses?
Colon cancer is cancer that affects the part of digestive system. So definitely effects a persons digestive system. Some of the colon cancer symptoms are Blood (usually dark red or black) in the stool, Constipation and diarrhea, Long, thin, pencil-like stools, Fatigue and weakness, Abdominal pain or bloating, Unexplained weight loss. These symptoms worsens as the colon cancer progresses.
Consult an oncologist, who on examining the patient will answer all your queries. Hope our answer helps you.
Answered on 23rd May '24
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What is to be done after immunotherapy and elevated liver enzyme levels when seen?
Male | 44
If yellowing of eyes, dark urine, pale stool seen, get your SGPT and SGOT tests done
Answered on 23rd May '24
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My mother 56 yr old is a breast cancer survivor ...its been 1.5 yrs since she is cancer free ...she is suddenly facing body ache and loss of appetite similar to what she used to face after chemotherapy .what is the reason behind it
Female | 56
These symptoms could be related to the chemotherapy or may be due to another underlying condition. It is important to get a proper diagnosis from a specialist who has knowledge of her medical history and current condition. It is advisable for your mother to consult her oncologist regarding her body ache and loss of appetite.
Answered on 23rd May '24
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Lump under armpit - thought I had a muscle strain, go to check my armpit where the pain is and there’s a hard edamame size lump. This shoots ache down my arm and the location under pit is painful. Warm compress is all I’ve done.
Female | 23
That may be a symptom of the breast infection, cyst or even cancer. In this situation, a specialist to refer to is an oncologist or a breast surgeon. The application of warm compress might give just the temporary relief of the pain, but it is critical to see a doctor as soon as possible.
Answered on 23rd May '24
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Melanoma skin cancer in stage 4 . How I increase survival rate
Female | 44
Stage 4 melanoma skin cancer means the disease has moved to other body parts. You may notice weird moles, spots that change, and feel unwell. Too much sunlight exposure causes it. Treatments like surgery, chemo, immunotherapy, and targeted therapy help. But survival rates rise by listening to your oncologist and checking regularly.
Answered on 28th Aug '24
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My mother is Squamous cell carcinoma on the tongue for one and half year now..Please guide me for cheap treatment as we dont have much money (Name: Jatin)
Please provide with all the reports along with scans we'll try and help you partly in financially sustaining treatment through our partner NGOs. Reports are needed.
Answered on 23rd May '24
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Patient Name: Nayan Kumar Ghosh Age :+57 Yrs I am Sangita Ghosh from Bangladesh. Recently My father was suffering with sparing of Anti Commissure (right vocal Cord ) . after that. He had done his operation by Dr. N. V. K Mohan (ENT Specialist ) in Medica Superspecialty Hospital , Kolkata. After surgery Doctor said that it would be pre- cancerous disease in the throat according to the biopsy report . SO , We need a Second opinion before going through the Radiography process or something . One more thing is that, for doctor consultation , is it mandatory to require Medical Visa ??? In this circumstance, please suggest me the best doctor who is the expert of Oncologist in India so that my father can get proper treatment as soon as Possible .
Answered on 23rd May '24
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Why Is radioactive iodine necessary after a thyroidectomy?
Female | 44
Yes, it's necessary to destroy any remaining thyroid tissue or cancer cells and to monitor the effectiveness of treatment.
Answered on 23rd May '24
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